South Africa head coach Heyneke Meyer (inset) subscribes to Steven Hansen's view that there is no psychological advantage to be gained from storming Twickenham so close to next year's World Cup.
All but two quarter-finals and the bronze final of England 2015's knockout phase is being staged at the venue, prompting Stuart Lancaster's men to highlight the importance of turning their home ground into a fortress this autumn.
New Zealand departed with a 24-21 victory in last weekend's opening QBE International but Hansen, their head coach, described the idea the win would have lasting ramifications for the World Cup as a "load of baloney".
Meyer goes a step farther by insisting the experience generated from playing England is more important than the result - win, lose or draw.
"I truly believe what happens now will not have a big influence on the World Cup," Meyer said.
"In a sense it's almost better if you lose as your guys will then know they will have to step it up. I'm not saying we should lose of course, but there are so many nuances.
"You can't say because you have won at Twickenham you now have the edge next time because you then get complacent. The World Cup is a different thing.
"If you look at 2007 when South Africa won the World Cup, they lost a lot of games that year and that didn't make a huge difference."
South Africa are undefeated by England in 11 matches dating back to 2006 when they succumbed 23-21 at Twickenham and Meyer admits his team talk on Saturday will be brief.
"We are fired up for every game, but it's always special playing England. We are always nervous whenever we play them and you need to turn those nerves into excitement," Meyer said.
"You don't have to motivate the guys against England. They know it's a huge challenge and they know there's an unbelievable heritage going back so many years.
"This week we don't have to say anything - we know the players will be motivated. It will be an unbelievable atmosphere, a real pressure cooker."
Meyer has made five changes to the starting XV defeated 29-15 by Ireland last Saturday, but retains the same 23.
Wing JP Pietersen, flanker Schalk Burger, scrum-half Cobus Reinach, fly-half Pat Lambie and hooker Adriaan Strauss have been promoted from the bench with Meyer insisting the adjustments were pre-planned and not a response to events in Dublin.
"You are going to lose games, even if you're South Africa. Ireland was one of those strange games - we won everything except on the scoreboard. The result was a wakeup call for me as a coach and for the team as well," he said.
"There's no shame in losing, but I was ashamed by our performance. We have to learn from that. We can't make the same mistakes again.
"The one thing we are not good at is our kicking game and the contestables. England and New Zealand are very good at that.
"We have been the best in the world at that, but as a nation we have fallen behind."