Frankel is one of the headline names among 43 entries for the Juddmonte International at York.
Henry Cecil's three-year-old star is now undefeated in seven starts, including wins in the 2000 Guineas and St James's Palace Stakes on his last two runs.
However, he has yet to race beyond a mile and would be a fascinating contender if he lines up over 10 furlongs on the Knavesmire.
Frankel is owned by Khalid Abdullah and he also has multiple Group One winners Midday, Workforce and Twice Over among his other possible challengers.
Aidan O'Brien has made his usual strong entry headed by Hardwicke Stakes hero Await The Dawn and ex-Australian star So You Think.
He has entered a total of 15 horses including St Nicholas Abbey, Zoffany and Misty For Me.
Godolphin is another team with plenty of possibles, with Prince of Wales's Stakes winner Rewilding in the squad.
Lady Of The Desert will miss the Darley July Cup after taking longer than expected to recover from an injury problem.
The four-year-old is yet to make her seasonal bow after emerging as a leading candidate for sprint honours when winning the Diadem Stakes at Ascot last year before finishing second in the Prix de l'Abbaye.
Trainer Brian Meehan had hoped to run the filly in the Golden Jubilee at Ascot but a splint saw her miss that date and will keep her on the sidelines.
"Lady Of The Desert is set to miss the July Cup," Meehan said. "The injury which held up her preparation for Royal Ascot is taking a little longer than expected to resolve and she will not be ready in time for the July Cup.
"Her key target will be the Betfred Sprint Cup at Haydock."
A total of 30 horses have stood their ground including Golden Jubilee hero Society Rock.
Australian colt Star Witness also features along with Markab, Kingsgate Native, Monsieur Chevalier and Sole Power.
Godolphin's Delegator, who was forced to miss Ascot due to the soft ground, is the ante-post favourite for the July 9 contest.
Sri Putra once again looks set to tackle top-class middle-distance opposition in the Coral-Eclipse at Sandown on July 2.
Roger Varian's five-year-old was beaten just half a length by Twice Over in the 10-furlong Group One last year, and could again take his chance after finishing third behind Rewilding and So You Think in the Prince of Wales's Stakes at Royal Ascot.
"I thought he ran well and he is a horse who seems to be at his best over a strongly-run 10 furlongs on a stiff track," said Varian. "He got beaten in a conditions race at Lingfield the time before, but he probably needed the run a bit and those smaller field races where they go no gallop just suit him.
"He has come out of Ascot well and we're entitled to consider the Eclipse. We went into Ascot open-minded and we could do the same going to Sandown.
"He was 66-1 at Ascot and you start to doubt yourself going there, but he showed running him in these races is not pie in the sky.
"So You Think and Workforce could both run in the Eclipse, but if it looks like there will only be a handful of runners, we might be there."
Workforce was in action on the Long Hill chippings at Newmarket yesterday.
Michael Stoute's charge worked in company with his usual lead horse Confront over four furlongs.