The Government will be writing to their UK counterparts and sports broadcasters expressing "outrage" at gang boss Daniel Kinahan's involvement in the boxing showdown between Tyson Fury and Anthony Joshua.
Junior sports minister Brendan Griffin made the announcement in the Dail last night.
The Fine Gael TD said he was "absolutely appalled" to see what has surfaced in the last 24 hours, alluding to the proposed two-fight deal reputedly brokered by Kinahan between the two English world heavyweight champions.
"I have today asked officials in my department to draft letters to my counterpart in the UK; also to the broadcasters, Sky and BT, to express our outrage about this situation. It's completely unacceptable," he said.
"My heart goes out to the decent volunteers and participants in boxing around the country who give so much time and effort to their communities.
"Sport Ireland has no connection with professional boxing, but they want to emphasise that in relation to amateur boxing in this country, there is no question whatsoever of any link to criminality.
"I think the danger is here that the reputation of Irish boxing would be tarnished because of this incident, and that's grossly unfair to the huge number of people who do great work."
Mr Griffin's comments were echoed by Sports Minister Shane Ross, who highlighted the "unparalleled" work of amateur boxing volunteers.
"It would be absolutely wrong - tragic - if their name was sullied by activities which are completely and utterly unacceptable," Mr Ross added.
It comes after Taoiseach Leo Varadkar said the Department of Foreign Affairs has been in contact with the United Arab Emirates (UAE) authorities about Kinahan after he was praised by Tyson Fury.
Mr Varadkar said he was "taken aback" to see the crime boss name-checked.
He made the remarks in the Dail as the Government was asked to contact the UAE about Kinahan (42) who is based in the country.
Fury thanked Kinahan for brokering the fight deal with Joshua in a video posting.
Labour Party leader Alan Kelly said: "There's an individual from our country who according to the High Court is a very senior figure in organised crime on a global scale and according to CAB has controlled and managed operations of the Kinahan organised crime group for some time.
"He's now rebranded himself in the Middle East as a boxing promoter and one of the most famous individuals involved in that has described him as a smart, able and honest man.
"We have to, through the Department of Foreign Affairs, intervene with the UAE in relation to this individual.
"We owe it to the victims of such a cartel."
Addressing Mr Varadkar, he added: "I would ask you, through the Department of Foreign Affairs, to highlight how important this is for us because of the parasitical criminal activities of this individual and all associated with him."
Mr Varadkar said: "I don't want to say too much about it but I have to say I was rather taken aback to see Tyson Fury and his video the other day - just dropping in that name that you mentioned as if this was not somebody who has a quite a chequered history in this State and elsewhere.
"While I can't comment on any particular garda operation, I can certainly assure you there has been contact between the Department of Foreign Affairs and the authorities in the United Arab Emirates."
In a video posted on his social media accounts on Wednesday, Fury announced a two-fight deal between him and unified world title holder Joshua.
"I'm just after getting off the phone with Daniel Kinahan," he told his followers, adding: "He's just informed me that the biggest fight in British boxing history has just been agreed."