IRFU: Sean O'Brien and Jared Payne suffered concessions in England win
The IRFU has confirmed that Sean O'Brien and Jared Payne were concussed in the win over England. Both players have started graded return to play protocols.
Johnny Sexton has also suffered a minor hamstring injury according to the IRFU's latest injury update.
Sexton (hamstring) and O'Brien (concussion) are Ireland's most significant doubts ahead of the Six Nations showdown against Wales in Cardiff on Saturday week.
Coach Joe Schmidt will have to take a wait-and-see approach as O'Brien was withdrawn as early as the 24th minute of yesterday's 19-9 victory over england at the Aviva Stadium.
Sexton followed suit on conversion of centre Robbie Henshaw's try in the 54th minute.
Out-half Sexton was immaculate once again as he led Ireland out to a 19-3 lead before what Schmidt called a "twinge" prompted his removal.
The loss of both would dramatically reduce Ireland's chances without their primary playmaker and their enforcer-in-chief in the pack.
The back row will probably have to cope without No 8 Jamie Heaslip, although his initial assessment of 4-6 weeks from three fractured vertebrae in his back gives him an outside shot at making it.