Weekend rumours had linked O'Neill with a new role alongside former teammate Brian Mullins, who remains the name on most people's lips to succeed Paul Caffrey.
"That's news to me," said the last man to lead Dublin to All-Ireland glory, 13 years ago. "I am certainly not involved and I don't know if Brian Mullins is involved. I know he has been asked about it but I don't know what his reply is."
The leading medic stressed that he's "not available" for a management role because of work and other academic commitments that take up a lot of his time. "The same applies to a lot of people who would love to do it but don't have the time," he added.
However, O'Neill confirmed that he has agreed to get involved in a committee searching for a new manager, and he will play a role in the interview process.
O'Neill was a '70s teammate of Mullins but is most revered in Sky Blue circles for managing the county to the summit in 1995, ending a 12-year famine without Sam. He duly stepped down, and Dublin have now gone 13 years without another All-Ireland title.
Most speculation has centred on Mullins, although he has never publicly declared whether he's interested in a return to inter-county management.