The Liveline host has published the first ever comprehensive list of children and wants to gather more information about their short lives.
The youngsters – aged 16 and under – were nearly all killed in crossfire during street battles.
"There were 30 children killed during the week of the Easter Rising. Most of them were killed in crossfire; most of them were killed within a mile radius of O'Connell Street.
"There were two two-year-olds killed on Easter Monday, one of them was in his pram," Joe told the Herald.
"I'm publishing a booklet with as much as I can find on each child. They were children, they had no direct descendants."
Of the 450 people killed in the "six-day war", 260 were civilians including the 30 children; 65 were rebels; and 116 were soldiers, he pointed out.
"Where are the relatives of the children killed? Some names are very distinctive – Fetherstone, Warbrook, Sainsbury. Hopefully, it will jog people's memories.
"The Rising came unexpectedly obviously. People were locked in their homes... when the Rising was going on, who went to get food, bread or milk? The people who made a run for it were the teenagers."
He was prompted to research the subject when children's charity the Jack & Jill Foundation asked him to get involved with its public art project.
The RTE presenter was given a glass Easter egg to paint and decided to print the names of the children who were killed.
"I expected to pick up a history book and read it but there was no full list," Joe said.
"We've never had a commemoration of the children who died in the Rising."
He hopes to publish his booklet, Children of the Revolution, next week and urged the public to contact him at email@example.com.