The controversial singer warned of a "f ***in bloodbath" if Pope Benedict was to visit Ireland. The threat is the latest in a string of comments made by the troubled singer on the internet which have led to concerns among friends over her state of mind.
Reacting to a radio poll on a potential visit by the Pope, O'Connor – who caused worldwide fury in 1992 when she ripped up a photo of Pope John Paul on US television – warned that there would be a "f **kin bloodbath". "'Young people of Ireland I love u' said Sinead as she pulled the f ***ing trigger," the singer wrote on Twitter.
"There'd be a f**kin bloodbath. Me meet the f **ker off the plane myself," she added. One senior bishop today described the comment as "extreme" and pleaded for "those around Sinead to help her."
"There'd be a f**kin bloodbath. Me meet the f**ker off the plane myself."
The comments have again led friends of the singer to raise concerns about her mental state.
Antrim Bishop Pat Buckley today told the Herald that the comments were "extreme" and showed that the singer was "incredibly vulnerable".
"This is extreme language and it's very worrying," he said.
"I spoke to Sinead a while ago and she's an incredibly talented person. She's a genius in fact. But she's clearly very vulnerable. We cannot condone that type of language, they are very extreme words to use.
"I would hope that if there are people close to her, that they will support her during this time. She appears by her comments that she's near the edge."
Bishop Buckley said that Sinead had done "wonderful work" in helping people in the past and that he hopes she can "get her life back on track".
"I remember the work she did with the poor, the homeless, the drug addicts -- it was admirable. We cannot condemn her for expressing her views but they are worrying."
O'Connor infamously ripped up a picture of John Paul II live on American television in 1992 in protest against clerical abuse.
And fans of the singer bombarded her with messages of support on Twitter after she wrote that she wanted to be dead earlier this month.
The tweets prompted gardai to call to O'Connor's north Wicklow home following the suicide threats.
The mum-of-four admitted she was broken-hearted after her marriage breakdown and had been seeing a psychiatrist.
"Now I wish I was dead. No hope," she said. "Anyway ... If anyone knows how I can kill myself without my kids finding out I did it deliberately please tell me."
Sinead split from her third husband Steve Cooney last April after a year of marriage.
One fan pleaded with Sinead to stay strong: "So much love out there for you," they wrote.
"If anyone knows the lovely, clever, funny Sinead O'Connor can they go and give her the hugest hug," another wrote.