Both the character and Threlfall are committed fans of the club.
Programme makers are putting the finishing touches to the finale of the series which will return to screens for the last time in spring.
Original cast members such as Ann-Marie Duff will return for the climax of the 11th series. Take That star Jason Orange will also make a cameo appearance during one of the episodes, playing a DJ called Scouse Mouse who sets up a festival on the Chatsworth estate.
"It is a life changing moment for Frank Gallagher and David Threlfall," a spokeswoman for the show said of the visit to the stadium.