The late star -- who died 17 months ago -- previously took the title in 2007 on the back of her massive Back To Black album.
Emeli Sande, Mumford And Sons and Mercury Prize-winners Alt-J lead the nominations for next month's Brits, competing for three each.
Muse, Plan B, Rita Ora, Coldplay and Olly Murs are among eight acts with two nominations apiece.
The Rolling Stones have been nominated for best live act -- the first time they have been in the running for a Brit for 17 years.
The big award of the night, best album, will be fought between Sande's Our Version Of Events, Alt-J's An Awesome Wave, the Mumford release Babel and Plan B's Ill Manors. Paloma Faith is also up for the title for her second album, Fall To Grace.
Sande and Faith go up against each other once more in the British female category, with BatS For Lashes (Natasha Khan), Jessie Ware and Winehouse completing the contenders. Sande's final nomination is as one of the 15 tracks up for best single with Next To Me.
The nominations were announced at a ceremony in London's Savoy Hotel last night, which saw the first 2012 Brit trophy -- designed by artist Damien Hirst with his signature spot design -- handed to critics' choice winner Tom Odell.