The report had been sealed at the request of detectives until last week, Chief Coroner Investigator Craig Harvey said. The 23-page report details the trajectory of each of the shots that hit the rapper, whose name was Christopher Wallace. Investigators determined that a single shot that hit his left lung, heart and colon led to the 24-year-old's death.
No drugs or alcohol were found in his system, the report states.
The rapper from Brooklyn, New York, had just left a music industry event when he was shot. Los Angeles police and the FBI have investigated the killing, but no arrests have ever been made. Neither agency had any immediate comment on the release of the report.
A lawyer for Wallace's family and widow Faith Evans did not immediately return a phone message seeking comment.
Federal agents conducted a bi-coastal search for Wallace's killer, but federal prosecutors determined in 2005 that there wasn't enough evidence to pursue a case.
Agents looked into whether any Los Angeles police officers had been involved in the shooting, which came months after another rap superstar, Tupac Shakur, was shot dead in Las Vegas.
In March 2011, the FBI electronically released files on its investigation, which were heavily redacted but shed new light on the efforts that investigators took to try to find those responsible for the rapper's death.
The deaths of Wallace and Shakur have been the subject of rampant speculation about the motives. The one-time friends became rivals and instigators in an East Coast-West Coast rap rivalry during the mid-1990s.