Magazine readers are in for a surprise as the cover depicts the three blondes completely unclothed.
Further inside the magazine they are joined by up-and-coming model Jude Nabney and Dublin Fashion Week organiser Sonia Reynolds, who also agreed to take part.
"The idea of the photo shoot was to reveal the 'naked truth' of women in differing age groups between the 20s and 50s," said editor Laura Bermingham.
"The magazine looks at real women with real issues," she continued. "It tackles serious issues, women's health and problems that we all experience.
"It's for women of all ages who are not necessarily a size zero.
"I've noticed that women are frustrated by the lack of information about issues that concern them. There is no information for women over the age of 45," she said.
This view is echoed by publisher Marie Loftus, who has enjoyed success with a stable of health and beauty titles.
According to the publisher, the magazine photographed the cast of "strong, powerful Irish women" in a glamorous photo shoot to reveal their "individual naked truth".
"Whether it's sex or surgery, relationships or reiki, menopause or make-up, glow's mission is to unearth and reveal the 'naked truth' about real issues affecting Irish women today," she said.
Both Laura and Marie stress that the magazine "is not an overnight celebrity magazine" and it hopes to differentiate from other publications on the shelves by offering candid and in-depth articles that are designed to educate rather than entertain.
The magazine will also have a website where readers can blog their experiences and contribute feedback. Laura says this could make up part of the content, although celebrities and experts will feature heavily.
Laura has been one of Ireland's top models for over 15 years and has worked as a contributor on TV3 show Ireland AM since 2004.